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RNAi: antiviral therapy against dengue virus

Jan 20, 2013 ... [18] Martínez MA. RNA interference and viruses: Current innovations and future trends. United Kingdom: Caister Academic Press. 2010. [19] Jeang KT. RNAi in the regulation of mammalian viral infections. BMC Biol 2012, 10: 58. [20] Haasnoot J, Berkhout B. RNA interference: its use as antiviral therapy.

apjtb-03-03-232.pdf

RNA Interference: Past, Present and Future

in living systems, the development of anti-viral and anti- cancer therapies, and genome-wide screens. In this review, we discuss the landmark discoveries that established the contextual framework leading up to our current understanding of RNAi. We also provide an overview of current developments and future applications.

1.pdf

Review The promise, pitfalls and progress of RNA- interference

Feb 3, 2012 ... The promise, pitfalls and progress of RNA- interference-based antiviral therapy for respiratory viruses. John P DeVincenzo1,2,3,4*. 1Department of Pediatrics, University of Tennessee Health .... present value of a programme and shortens development ...... and viruses: current trends and future innovations.

46fa70c089e7fce5b58b5084dcda77e55b52.pdf

Antiviral Gene Therapy Research Unit, Department of Molecular

hepatitis B virus infection, In: RNAi and Viruses, Current Innovations and Future Trends, Ed,. Martinez MA, Horizon Scientific Press, UK, pp143-160. 32. Chattopadhyay S., Ely A., Bloom K.,Weinberg M.S. and Arbuthnot P. (2009) Inhibition of. Hepatitis B virus replication with linear DNA sequences expressing antiviral micro ...

CV-Prof-Arbuthnot.pdf

Antisense Phenotypes Reveal a Functional Expression of OsARF1

pathogenesis , comprehensively covering all the recent advances. RNA Interference and Viruses. Current Innovations and Future. Trends. Edited by: Miguel Angel Martínez c. 280 pp., February 2010. ISBN: 978-1-904455-56-1 $310 / £159. Expert RNAi specialists from around the world have teamed up to produce a timely.

60529727.pdf

The Hepatitis C Virus NS2/3 Protease

pathogenesis , comprehensively covering all the recent advances. RNA Interference and Viruses. Current Innovations and Future. Trends. Edited by: Miguel Angel Martínez c. 280 pp., February 2010. ISBN: 978-1-904455-56-1 $310 / £159. Expert RNAi specialists from around the world have teamed up to produce a timely.

The-hepatitis-C-virus-NS2-3-protease.pdf

The Interactions of the Largest Subunit of RNA Polymerase II with

pathogenesis , comprehensively covering all the recent advances. RNA Interference and Viruses. Current Innovations and Future. Trends. Edited by: Miguel Angel Martínez c. 280 pp., February 2010. ISBN: 978-1-904455-56-1 $310 / £159. Expert RNAi specialists from around the world have teamed up to produce a timely.

60566067.pdf

Green Technologies for Room Temperature Nucleic Acid Storage

pathogenesis , comprehensively covering all the recent advances. RNA Interference and Viruses. Current Innovations and Future. Trends. Edited by: Miguel Angel Martínez c. 280 pp., February 2010. ISBN: 978-1-904455-56-1 $310 / £159. Expert RNAi specialists from around the world have teamed up to produce a timely.

Green-Technologies-for-Room-Temperature.pdf

Antivirals — current trends in fighting influenza

Review. Antivirals — current trends in fighting influenza. Ewelina Król1✉, Małgorzata Rychłowska2 and Bogusław Szewczyk1. 1Department of Recombinant Vaccines, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk,. Gdańsk, Poland; 2 Department of Virus Molecular Biology, ...

495.pdf

The RNAi pathway plays a small part in Wolbachia-mediated

Mar 6, 2017 ... stranded RNA virus of the family Flaviviridae and the causative agent of dengue fever, a debilitating illness and ... Current vaccines are imperfect10,11 and there are no effective antivirals. .... A. aegypti cells by manipulating gene expression via targeted RNAi techniques in both Wolbachia-infected and.

srep43847.pdf?origin=ppub

Strong Resistance Against Rice grassy stunt virus Is Induced in

Current address of T. Sasaya: Kyushu Okinawa Agricultural Research Center, Koshi, Kumamoto 861-1192, Japan. Accepted for publication ... findings obtained from an RNAi experiment with Rice stripe virus (RSV), a tenuivirus ..... Engineering pathogen resistance in crop plants: Current trends and future prospects. Annu.

PHYTO-07-12-0165-R

View PDF

pathogenesis , comprehensively covering all the recent advances. RNA Interference and Viruses. Current Innovations and Future. Trends. Edited by: Miguel Angel Martínez c. 280 pp., February 2010. ISBN: 978-1-904455-56-1 $310 / £159. Expert RNAi specialists from around the world have teamed up to produce a timely.

Interplay_between_human.pdf

Therapeutic application of RNAi: is mRNA targeting finally ready for

Dec 12, 2007 ... 17). Instead, the purpose of the current article is to highlight some of the recently emerging innovative strategies to overcome two general but highly critical hurdles on the way to clinical RNAi translation: delivery and safety. For the first, we will put particular focus on the increasing role of viral-based RNAi.

20080728_1ee47fb0b074fcd0f7cecBrTWT1ucm9a.attach.pdf

Engineering Pathogen Resistance in Crop Plants: Current Trends

May 5, 2010 ... Engineering Pathogen. Resistance in Crop Plants: Current Trends and. Future Prospects. David B. Collinge, Hans J.L. Jørgensen,. Ole S. Lund, and Michael F. Lyngkjær ... For viruses, RNA interference is increasingly being used. 269 ... lobby group whose mission is to “promote an innovative and dynamic ...

ref-id-28.pdf

Crop Protection Contributions toward Agricultural Productivity

The Need for Agricultural Innovation to. Sustainably Feed the World by .... TRENDS—CURRENT AND. FUTURE. Plant Pathogen Management with Fungicides. The development of fungicides to combat plant pathogens dates back to the mid-1600s, and our ..... or sprayable RNAi products against viral and fungal pathogens ...

CAST_IP58_Crop_Protection_928EF2BE98D19.pdf

Top 10 Emerging Technologies of 2015

the ringspot virus, for example, with no sign of resistance evolving in over a decade of use in Hawaii. RNAi may also benefit major staple-food crops, protecting wheat against stem rust, rice against blast, potato against blight and banana against fusarium wilt. Many of these innovations will be particularly beneficial to.

WEF_Top10_Emerging_Technologies_2015.pdf

ALN-HBV, an Investigational RNAi Therapeutic for the Treatment of

Jul 28, 2015 ... future results, performance or achievements expressed or implied by these forward-looking statements. ... Alnylam RNAi Therapeutics Strategy ..... HBV. cccDNA. TREATMENT. Lifelong suppression. HIV. Proviral DNA. HCV. Viral RNA . TREATMENT. No reservoir of infection. ↓. HCV clearance. ↓. CURE4.

ALN-HBV_RNAi_Roundtable_072815.pdf

RNAi Booklet.ps

have been achieved in animal models, the development of new and innovative tech- niques is ... yet known, it presumably involves a species of nucleic acid homologous to the viral target. Similarly, spreading of the RNAi signal beyond the initial site of in- oculation is .... C. Cogoni and G. Macino, Trends Plant Sci. 2, 438  ...

RNAi.pdf

Anti-HIV activity prediction and enrichment identify novel human

Jul 4, 2017 ... Abstract. Human immunodeficiency virus (HIV) relies heavily on the host proteins to facilitate its entry and replication. ... viral-host protein interactions by proteomics, RNA interference (RNAi), CRISPR screen, microarrays, peer- reviewed) is ..... Development: Current Innovations and Future Trends. Journal of  ...

159236.full.pdf

Genome-Wide RNAi Screen for the Discovery of Gene Function

Plant RNAi forms the basis of virus induced gene silencing (VIGS), proofed from the genetic links between ... post-genome era, utilizing high-throughput platforms and innovative bioinformatics tools, many large-scale RNAi ..... Furthermore, the results from RNAi screen can be used to design future theroputic drugs and crop  ...

InTech-Genome_wide_rnai_screen_for_the_discovery_of_gene_function_novel_therapeutical_targets_and_agricultural_applications.pdf