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Profiles Drug. Subst., 1980,9, I (rev). Toscano, W.A. et al, Pharmacol. Ther., 1982, 16, 199 (pharma- col, rev). Froeyshov, 0., Drugs Pharm. Sei., 1984, 22, 665 (isol, props, rev). Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th. Ed., Akademie-Verlag, Berlin, 198 7, 8368. Martindale, The Extra Pharmacopoeia, ...


Simple Copper Salt-Catalyzed N-Arylation of Nitrogen-Containing

M. In Organic-Chemical Drugs and their Synonyms: An International. SurVey, 7th ed.; Akademie Verlag GmbH: Berlin, Germany, 1994. (d). Kundu, N. G.; Mahanty, J. S.; Chowdhurry, C.; Dasgupta, S. K.; Das, B.;. Spears, C. P.; Balzarini, J.; De Clercq, E. Eur. J. Med. Chem. 1999, 34,. 389. (e) Kunz, K.; Scholtz, U.; Ganzer, ...


Selective N-alkylation of indoles with primary alcohols using a Pt

Sep 9, 2014 ... 5 M. Negwer and H.-G. Scharnow, Organic-Chemical Drugs and Their Synonyms , Wiley-VCH, Weinheim, 9th edn, 2007, vol. 3, p. 1915. Scheme 2 Presumable pathways of N-alkylation (by Pt/HBEA) and C3-alkylation (by Pt/Al2O3)18 of indole with primary alcohols. Communication. Green Chemistry.


Copper-Catalyzed Coupling of Alkylamines and Aryl Iodides: An

heterocycles,9 and hydrazides10 as well as the preparation of diaryl ethers11 have been reported. Progress in the arylation. (1) Negwer, M. In Organic- Chemical Drugs and their Synonyms: (An. International SurVey), 7th ed.; Akademie Verlag: Berlin, 1994. (2) For reviews, see: (a) Yang, B. H.; Buchwald, S. L. J. Organomet.


Chemical Synonyms, Molecular Structure and Toxicological Risk

Feb 25, 2016 ... J Develop Drugs. ISSN: 2329-6631 JDD an open access journal. 34. Al-Sabti K ( 2000) Chlorotriazine reactive Azo red 120 textile dye induces micronuclei in fish .... Appendix 1: Effects of different groups of Textile dyes, their synonyms and chemical structures: review of studies reported in the literatureA. No.


1 Markovian chemicals “in silico” design (MARCH-INSIDE), a

Here, 3D-MARCH-INSIDE molecular descriptors for 667 organic compounds are used as input for a Linear ... Chemicals-In silico-Design (MARCH-INSIDE) has shown to be very useful in drug design, toxicology, proteomics, and ..... Negwer M (1987) Organic chemical drugs and their synonyms, Akademie-Verlag,. Berlin. 31 .


Phenytoin I: In Vitro-In Vivo Correlation for 100-mg Phenytoin

(1) M. Negwer, “Organic-Chemical Drugs and Their Synonyms,”. (2) M. Majchrzak , A. Kotebo, and R. Guryn, Pol. J. Chem., 53,2135. (3) M. W. Majchrzak, A. Kotefio, R. Guryn, J. B. Lambert, and S. (4) R. Guryn, A. Kotefio, M. Majchrzak, A. Szadowska, and I. Wej-. (5) A. Szadowska, M. Mazur, J. Graczyk, M. B. Kierek, R. Guryn, ...


New Antitrichomonal Drug-like Chemicals Selected by Bond (Edge

in ovariectomized Wistar rats achieving promising results as a trichomonacidal drug-like compound. (Journal .... organic chemicals having as much structural variability as ... All these chemicals were taken from the Negwer handbook18 and Merck Index,19 where their names, synonyms, and structural formulas can be found.


Overview of the chemical compound and drug name recognition

as medicinal chemistry, biochemistry, organic chemistry and toxicology. A total of 27 teams – 23 ... effects of chemical compounds and their associations to toxicological endpoints, or the extraction of pathway .... Chemical compounds/ drugs often have many synonyms or aliases (e.g. system- atic names, trivial names and ...


Synthesis and Oral Hypoglycemic Activity of 3-[5'-Methyl-2'-aryl-3

clinically used potential drug candidates showing oral hypoglycemic and ... other chemical classes of drugs which may increase the production of Insulin. The chemical compounds like sulphonyl ureas, biguanides, thiazolidinediones ..... Negwer M, Organic-Chemical Drugs and Their Synonyms, 6th Ed., Akademie- Verlag,.


Heterogeneous Route for the One-Pot Synthesis of N-Arylamides

Dec 1, 2017 ... Department of Chemistry, University of Calcutta, 92 A. P. C. Ray Road, Kolkata 700009, West Bengal, India. § ... these heterogeneous catalysts could be easily recycled and reused, showing potential application in organic synthesis. 1. ..... (1) Negwer, M. Organic-Chemical Drugs and Their Synonyms: (An.


I. . Chemical and Physical Information A. Synonyms: Xylan hydrogen

I. . Chemical and Physical Information. A. Synonyms: Xylan hydrogen sulfate, scxlium salt ... 'Ihe Food and Drug Administration has nominated Elmiron for chronic toxicity and carcinogenicity testing. St.tbnitted by .... (Lyman et al. , 1982) • Based upon its water solubility and its presumed very low vapor pressure, it will not be ...


Multilingual dictionary of Narcotic Drugs and Psychotropic

Precursors and Essential Chemicals under International Control covering the substances listed in the 1988 Convention4, ... Thesaurus, in form of a cross-index of drug names and their synonyms listed in the monographs (PART TWO); .... General term for any organic molecule produced by combining two alcohols: Isomers.


and Copper-Catalyzed Intramolecular

Aug 11, 2009 ... (1) (a) Craig, P. N. In Comprehensive Medicinal Chemistry; Drayton, C. J.,. Ed.; Pergamon Press: New York, 1991; Vol. 8. (b) Brown, E. G. Ring Nitrogen and Key Biomolecules; Kluwer: Boston, MA, 1998. (c) Negwar, M. In Organic. Chemical Drugs and Their Synonyms (An International Survey), 7th ed;.


(or -oxygen) bond formation under ligand-free and solvent-free conditi

(c) Negwer M, Organic–Chemical Drugs and Their. Synonyms: An International Survey, 7th Edn, (Akademie. Verlag, Berlin), 1994. (d) Broekkamp C L E, Leysen D B, Peeters W M M & Pinder. R M, J Med Chem, 38, 1995, 4615. 2 (a) Metal– Catalyzed Cross Coupling Reactions, edited by. Diederich F & Stang P (Wiley– VCH, ...

IJCB 47B(11) 1701-1706.pdf

recent progress in the chemistry of dihydropyrimidinones

and their applications in the field of drug research have stimulated the invention of a wide range of ... Aryl-substituted. 3, 4-dihydropyrimidin-2(1H)-one and their derivatives are an important class of substances in organic and medicinal chemistry. NH. O. N. H. O ..... their Synonyms, Akademie Verlag: Berlin, 2558 ( 1994).


Thermal behaviour of procaine and benzocaine Part II: compatibility

Aug 20, 2013 ... The drug- excipient interactions can affect drug dissolution and/or bioavailability or/and their therapeutic efficacy and safety. The mechanisms by which the excipients affect the stability of drug are chemical reactions, sorption of ..... Negwer M, Scharnow HG: Organic-chemical drugs and their synonyms,.


Journal of Chemical and Pharmaceutical Research, 2013, 5(7):204

Multicomponent reactions (MCRs) have recently received the attention of organic chemists because of the many advantages of these reactions offered over conventional multi-step synthesis as well as their potential applications in medicinal chemistry for the generation of diverse scaffolds and combinatorial libraries for drug ...


The synthesis and properties of N-substituted amides of 1-(5

LII/LIII, 2, 23-28, (1997/1998). [4] Brucato A., Coppola A.: Boll-Soc. Ital. Biol. Sper., 54, 1051 (1978). [5] Coffen D. L., Fryer R.: US Patent No. 3849434 (1974). [6] Witkowski J. T., Robins R. K.: J. Med. Chem. 16, 935 (1973). [7] Negwer M.: Organic-chemical drugs and their synonyms, I (1986). [8] Beyer H., Liebenow W.: Chem.


Vitamin D Handbook: Structures, Synonyms, and Properties Edited

Physical Properties of Polymers Handbook, 2nd ed. Edited by James E. Mark ( University of Cincinnati, OH). Springer Science + Business Media, LLC: New York. 2007. xx. +. 1076 pp. $349.00. ISBN. 978-0-387-31235-4. This edition of Physical Properties of Polymers Handbook is a mammoth undertaking with 63 chapters ...