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(NB-506) Potentiates the Neurotrophic Effects of Neurotrophin-3 by

factor by staurosporine and K-252a results from the attenuation of the activity of the Trk tyrosine kinase. Biochemistry 31:4034 – 4039. Rask CA and Escandon E (1998) Neurotrophin treatment of peripheral sensory neuropathies, in Neurotrophic Factors: Handbook of Experimental Pharmacology. (Hefti F ed) vol 134, ...



In: Hefti F (ed) Handbook of experimental pharmacology, vol 134. Neurotrophic factors. Springer, Berlin Heidelberg New York, pp 189–224. Article published online. Corley M, Kroll KL (2014) The roles and regulation of Polycomb complexes in neural development. Cell Tissue Res. doi: 10.1007/s00441-014- 2011-9.

CTR Instructions for authors 2016.pdf?SGWID=0-0-45-841120-p1078975

The Association of Serum Levels of Brain-Derived Neurotrophic

Jan 18, 2017 ... delirious and non-delirious acutely ill older medical inpatients,”. Age and Ageing, vol. 38, no. 3, pp. 326–332, 2009. [6] Y. Barde, “Biological roles of neurotrophins,” in Neurotrophic. Factors, P. Aebischer and F. Hefti, Eds., vol. 134 of Handbook of Experimental Pharmacology, pp. 1–31, Springer, Berlin, Ger-.


Psychopharmacology of atypical antipsychotic drugs: From the

Oct 6, 2014 ... Key words: atypicality, brain-derived neurotrophic factor, dopamine, glycogen synthase kinase-3β, serotonin. ATYPICAL ANTIPSYCHOTIC DRUGS (APD) or second-generation antipsychotics have been chiefly used for the treatment of schizophrenia. Typical APD or first-generation antipsychotics often.


Protein Aggregation as a Cause for Disease | SpringerLink

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 172) ... Understanding the nature of these protective mechanisms together with the understanding of factors reducing or deactivating the natural protection machinery will be crucial for developing strategies to prevent and treat these disastrous ...


Role of transforming growth factor-beta isoforms in regulating the

NGF was the first member of a family of small homodimeric proteins, termed neurotrophins, to be identified (Levi-Montal- cini and Angeletti, 1968; Thoenen and Barde, 1980). Work over the past forty years has shown that NGF plays an important role in the development and growth of sensory and sympathetic neurons.


Tetracycline-Controlled Genetic Switches | SpringerLink

Abstract. Unlike recombinase-mediated gene manipulations, tetracycline (Tet)- controlled genetic switches permit reversible control of gene expression in the mouse. Trancriptional activation can be induced by activators termed tTA (Tet-Off) or rtTA (Tet-On) in the absence and presence of Tet, respectively. The Tet-Off and  ...

optional TetOn TetOFF.pdf

Introduction: P2 Receptors

Abstract: The current status of ligand gated ion channel P2X and G protein- coupled P2Y receptor subtypes is described. This is followed by a summary of what is known of the distribution and roles of these receptor subtypes. Potential therapeutic targets of purinoceptors are considered, including those involved in ...


Review Article Perspectives on the Use of Stem Cells for Autism

1 Department of Experimental Medicine, Second University of Naples, Via S. Maria di Costantinopoli, 16-80138 Napoli, Italy. 2 Centre for Autism, ..... neurotrophic factor secreting cells from human adipose and bone marrow- derived stem cells,” Development, Growth &. Differentiation, vol. 55, no. 6, pp. 648–655, 2013.


Prostaglandin E2 induces vascular endothelial growth factor and

Factor and Basic Fibroblast Growth Factor mRNA ... fibroblast growth factor ( bFGF) gene expression by prostaglandin E2 (PGE2) in cultured rat Muller ...... Handbook of Experimental Pharmacology. Vol. 69. Berlin: Springer-Verlag; 1984: 311-365. 9. Flower RW, Blake DA. Retrolental nbroplasia-evidence for a role of.


Historical review: ATP as a neurotransmitter

Feb 17, 2006 ... Review. TRENDS in Pharmacological Sciences Vol.27 No.3 March 2006 ..... endothelium-derived relaxing factor (EDRF) (nitric oxide) and subsequent vasodi - ..... 23 Abbracchio, M.P. and Williams, M. (eds) (2001) Handbook of. Experimental Pharmacology: Purinergic and Pyrimidinergic Signal- ling. (Vol.

W8-AR-Historical review- ATP as a neurotransmitter-TINS-Burnstock-2006.pdf

tryptophan on motor activity in mice

30, 123--134 (1973). 9 by Springer-Verlag 1973. Effects of L-Tryptophan on Motor Activity in Mice. K. Modigh. Department of Pharmacology, University of GSteborg, GSteborg, Sweden. Received .... different times of the year, factors other than the effects of the different ..... In: Handbook of experimental pharmacology, vol.


Unifying Perspectives of the Mechanisms Underlying the

Department of Pharmacology and Toxicology, Robert C. Byrd Health Sciences Center, West Virginia University School of Medicine,. Morgantown, West ..... factors and serve as central intermediates in signal trans- duction from the ..... Handbook of Experimental Pharmacology (Trendelenburg U and Weiner N eds) vol.


Role of AP1 in ethanolinduced Nmethyldaspartate receptor 2B

Department of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA. Abstract. Activator ... factor. J. Neurochem . (2005) 95, 1332–1341. The N-methyl-D-aspartate (NMDA) receptor, an excitatory neurotransmitter receptor in the CNS, plays an important role in neuronal ...


Brain-derived neurotrophic factor is required for axonal growth of

Mar 20, 2015 ... Objective: Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal development, and the Bdnf gene produces two populations ... Southern California, Los Angeles, CA 90027, USA 3Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC ...


Bladder sensory physiology: neuroactive compounds and receptors

Apr 23, 2014 ... compounds and receptors, sensory transducers, and target-derived growth factors as .... (9) [Springer, Handbook of Experimental Pharmacology ...... Neurotrophic factors: from physiology to phar- macology. Pharmacol Res 26: 1– 15, 1992. 134. Venkatachalam K, Montell C. TRP channels. Annu Rev ...


Caffeine and Adenosine

mirror those caused by adenosine actions. For further details see Sebasti˜ao and Ribeiro, 2009 – Handbook of Experimental Pharmacology, 193, ... which dilates blood vessels and increases urine volume; and theophylline, which relaxes ..... neurotrophic factor, GDNF, in slowing or halting dis- ease progression through ...


The Purinergic System and Glial Cells: Emerging Costars in

Sep 3, 2014 ... 1 Department of Pharmacological and Biomolecular Sciences, Universit`a degli Studi di Milano, Via Balzaretti, 9-20133 Milan, Italy. 2 Department of Drug Discovery ... of bioactive factors including cytokines and neurotrophic factors [7], which in turn ... International. Volume 2014, Article ID 495789, 13 pages.


The Neurobiology of Pain: Developmental Aspects

Volume 7, Number 3, 2001THE NEUROSCIENTIST n REVIEW .... The release of neurotrophic factors upon tissue damage is a major factor in the ..... Mechanisms of central hypersensitivity. In: Besson J-M, Dickenson AH, editors. Handbook of experimental pharmacology, vol. 130, the pharmacology of pain. Berlin: Springer  ...


Chronic exposure to D -tetrahydrocannabinol downregulates

bDepartment of Experimental Animals, Weizmann Institute of Science, Rehovot, Israel. cDepartment of Entomology, The ... expression of brain-derived neurotrophic factor (BDNF), at both. mRNA and protein levels, in brain ...... In: Pertwee, R. (Ed.), Handbook of Experimental Pharmacology. Springer-Verlag, Heidelberg, pp.