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Managing Scientists. Leadership Strategies in Scientific Research

Molecular Biology in Medicinal Chemistry, Volume 21. Edited by T. Dingermann ( Johann Wolfgang Goethe-Univer- sity), D. Steinhilber (Johann Wolfgang Goethe- University), and. G. Folkers (ETH Zürich). Wiley-VCH, Weinheim. 2004. xxi +. 413 pp. 18 × 24 cm. $175.00. ISBN 3-527-304431-2. As both the series editors and ...


5 Recent Studies on Doxorubicin and its Analogues

Progress in Medicinal Chemistry - Vol. 21, edited by G.P. Ellis and G.B. West. 0 1984, Elsevier Science Publishers, B.V. ... MOLECULAR BIOLOGICAL EFFECTS OF DOXORUBICIN. Biological reduction. Membrane effects. Interaction with the nucleus. Effects on the immune system. Other effects. Resistance to doxorubicin.


Medicinal chemistry and pharmacology of gold compounds

August 1996 , Volume 21, Issue 4, pp 377–383 | Cite as. Medicinal chemistry and pharmacology of gold compounds ... After 60 years of chrysotherapy perhaps an improved understanding of the molecular and biochemical mechanism of gold compounds will provide the impetus for new advances in the medical use of gold  ...


Asian Journal of Biomedical and Pharmaceutical Sciences

Next issue: Volume 7 Issue 63. The journal publishes scholarly articles on the systems, policies, and practices that promote research and innovations in Biomedical and Pharmaceutical Sciences. This includes research in following fields. Biomedical Sciences: Anatomy, Physiology, Biochemistry, Molecular Biology, Cell ...


Altering the specificity of subtilisin B. Lentus by combining site

Bioorganic & Medicinal Chemistry Letters, Vol. 6. No. 21. pp. 2507-2512, 1996 ... Departments of Chemistr)fl and Molecular and Medical Genetics. University of Toronto, 80 St. George St., ... although molecular biological strategies for overcoming this restriction have been devised recently. 1 However, the latter procedures ...


Impact of Biological Science to Medicinal Chemistry

Editorial. Current Topics in Medicinal Chemistry, 2017, Vol. 17, No. 21 2335. EDITORIAL. Impact of Biological Science to Medicinal Chemistry. Traditional medicinal chemistry has been dominated by studying small organic ... plines, such as molecular biology, biochemistry, structural biology, bioinformatics, toxicology, phar-.


Sequence specific inhibition of DNA restriction enzyme cleavage by

1993 Oxford University Press. Nucleic Acids Research, 1993, Vol. 21, No. 2 197- 200. Sequence specific inhibition of DNA restriction enzyme cleavage by PNA. Peter E.Nielsen ... are of significant interest in medicinal chemistry and molecular biology since they may provide the tools for sequence specific modification of DNA ...


Analgesic, Anti-Inflammatory, and Antiplatelet Profile of Hydrazones

Oct 6, 2013 ... 2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard University, New Delhi 110062, India ... Hydrazones possess wide variety of biological activities such as anticonvulsant, antidepressant, analgesic, anti-inflammatory, ... nescent probes, and molecular sensors [1, 14, 15].


DNA microarrays in drug discovery

nature genetics supplement • volume 21 • january 1999. Most pharmaceuticals sold today have their origin in ... The advent of molecular biology and gene cloning techniques transformed drug discovery in the following ... drug target interaction and guide medicinal chemistry efforts. Although the molecular biology revolution ...


Prof. Dr. M. Iqbal Choudhary

DR. MUHAMMAD IQBAL CHOUDHARY. (Hilal-e-Imtiaz, Sitara-e-Imtiaz, Tamgha- ei-Imtiaz). International Center for Chemical and Biological Sciences. (H. E. J. Research Institute of Chemistry,. Dr. Panjwani Center for Molecular Medicine and Drug Research). University of Karachi, Karachi-75270. Pakistan. Tel: (92-21) ...


Curriculum Vitae

biotechnology for health” research program. Projects .... Synthesis, biological evaluation and molecular modeling of 1,2,3-triazole analogs of combretastatin. A- 1. ... trypanothione reductase. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, p. 5255-5258, ISSN: 0960-894X, doi:10.1016/j.bmcl.2011.07. 036.



The European Journal of Medicinal Chemistry (EJMECH) publishes studies on all aspects of medicinal chemistry, including organic synthesis; biological behavior; pharmacological activity; drug design;. QSAR; molecular modelling; drug-receptor interactions; molecular aspects of drug metabolism; pro- drug synthesis and ...


Medicinal Chemistry Publications

Raimundo, Brian C.; Boardman, Paul; Lanza, Guido; Griffin, John H. Bioorganic & Medicinal Chemistry Letters (2011), 21(9), 2692-2696. DOI:10.1016/j.bmcl. 2010.12.037. Design, synthesis and initial biological evaluation of a novel pladienolide analog scaffold. Gundluru, Mahesh Kumar; Pourpak, Alan; Cui, Xiaoli; Morris, ...



Senior Research Scientist, Medicinal Chemistry Department, September 1996– March 2000 ... Albany Molecular Research Singapore Research Centre, Pte. ..... Progress in Heterocyclic Chemistry: Gordon W. Gribble and John Joule, Eds.;. Pergamon: Oxford, 2003, Volume 15, 206–229. 21. “The Chemistry and Biology of ...


Small Angle X-ray Studies Reveal That Aspergillus niger

Mar 3, 2008 ... From the ‡Departments of Medicinal Chemistry and Biology, University of Copenhagen, DK-2100 Copenhagen, Denmark,. §Department of Systems Biology, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark, ¶ Department of Molecular .... VOLUME 283 • NUMBER 21 •MAY 23, 2008 ...


Media Pack 2018

Biotechnology. I Current Biotechnology. Current Physical Chemistry. Computational Chemistry. I Current Computer-Aided Drug Design. I Recent Patents on ..... weapersonahead selle-. E-pub Ahead of Schedule. Current Medicinal Chemistry. ISSN: 02-9-853 volume 17. Number 21, 2010 should you not want to receive any ...


Matrix-assisted laser desorption ionization time-of-flight mass

Nucleic Acids Research, 1993, Vol. 21, No. 14 3191-3196. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry: a powerful tool for the mass and sequence analysis ... dl- and trlammonium salts of organic or Inorganic acids to suppress peak ... Today synthetic chemistry and molecular biology allow the.


An integrated dataset for in silico drug discovery

Nov 25, 2016 ... need with an integrated systems biology dataset, developed using the Ondex data integration platform, for the ... arrest the decline in the productivity curve, pharmaceutical companies, biotechnology companies and academic ... Drugs based on novel chemistry still take 10-15 years to reach the market, and ...


Ingemar Pongratz Publication list ARTICLES INCLUDED IN THESIS

Journal of Biological Chemistry 266,16813-16817,1991. 2. Ingemar Pongratz, Grant ... Molecular and. Cellular Biology 13, 2504-2514, 1993. 4. Anna Berghard, Katarina Gradin, Ingemar Pongratz, Murray Whitelaw and Lorenz. Poellinger. .... Bioorganic & Medicinal Chemistry, Volume 21, Issue 14, Pages 4120-31, 2013.


Ing. Tibor Maliar, PhD.

1. Synthesis and. Biological. Evaluation of. 17 beta-Hydroxysteroid. Dehydrogenase Type 1 (17 beta-HSD1) Inhibitors Based on a Thieno[2,3- d] pyrimidin-4(3H)-one Core. Lilienkampf Annamaria; Karkola Sampo; Alho-. Richmond Sari; et al. JOURNAL OF MEDICINAL CHEMISTRY Volume: 52. Issue: 21 Pages: 6660-6671.